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Jane E Schupp Selected Research

Idoxuridine (Stoxil)

8/2013Quantitative analysis of the effects of iododeoxyuridine and ionising radiation treatment on the cell cycle dynamics of DNA mismatch repair deficient human colorectal cancer cells.
11/2007Probabilistic modeling of DNA mismatch repair effects on cell cycle dynamics and iododeoxyuridine-DNA incorporation.
4/2006Methoxyamine potentiates iododeoxyuridine-induced radiosensitization by altering cell cycle kinetics and enhancing senescence.
1/2006The interaction between two radiosensitizers: 5-iododeoxyuridine and caffeine.
10/2005Schedule-dependent drug effects of oral 5-iodo-2-pyrimidinone-2'-deoxyribose as an in vivo radiosensitizer in U251 human glioblastoma xenografts.
11/2004Differential radiosensitization in DNA mismatch repair-proficient and -deficient human colon cancer xenografts with 5-iodo-2-pyrimidinone-2'-deoxyribose.
2/2003Inhibition of base excision repair potentiates iododeoxyuridine-induced cytotoxicity and radiosensitization.

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Jane E Schupp Research Topics

Disease

8Neoplasms (Cancer)
08/2013 - 02/2003
3Colonic Neoplasms (Colon Cancer)
11/2007 - 02/2003
2Colorectal Neoplasms (Colorectal Cancer)
08/2013 - 04/2006
2Body Weight (Weight, Body)
10/2005 - 11/2004
1Breast Neoplasms (Breast Cancer)
07/2007
1Genomic Instability
08/2006
1Necrosis
04/2006
1Glioblastoma (Glioblastoma Multiforme)
10/2005

Drug/Important Bio-Agent (IBA)

7Idoxuridine (Stoxil)FDA LinkGeneric
08/2013 - 02/2003
3Pharmaceutical PreparationsIBA
02/2007 - 11/2004
3DNA (Deoxyribonucleic Acid)IBA
10/2005 - 02/2003
2methoxyamineIBA
04/2006 - 02/2003
2ropidoxuridine (IPdR)IBA
10/2005 - 11/2004
1BRCA1 ProteinIBA
07/2007
1Complementary DNA (cDNA)IBA
07/2007
1Thioguanine (Tioguanine)FDA Link
02/2007
1Proteins (Proteins, Gene)FDA Link
08/2006
1Caffeine (No Doz)FDA LinkGeneric
01/2006
1ThymidineIBA
02/2003

Therapy/Procedure

3Radiotherapy
08/2013 - 11/2004
1Drug Therapy (Chemotherapy)
02/2007